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Outcome Reporting Bias In Trials

Outcome Reporting Bias In Trials. Outcome reporting bias is a threat to evidence based medicine and contributes to waste in research. The ORBIT Outcome Reporting Bias In Trials study outcome reporting bias was suspected in at least one trial in more than a third 96283.

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In the medical research field it is well known that clinical trials achieving statistical significance are more likely to be submitted and accepted for publication. Selective reporting of outcomes can bias clinical trials. This sort of within-study publication bias is usually known as outcome reporting bias or selective reporting bias and may be one of the most substantial biases affecting results from individual studies Chan 2005.

To provide information on the frequency and reasons for outcome reporting bias in clinical trials.

34 of Cochrane systematic reviews. Selective reporting of outcomes can potentially compromise the validity of a trial and any subsequent meta-analyses. 1 This happens when investigators publish some prespecified outcomes but not others depending on the nature and direction of the results. To provide information on the frequency and reasons for outcome reporting bias in clinical trials.